| 薄层色谱扫描法同时测定增效联磺片中三组分含量的研究 |
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| 引用本文： | 冯彦琳,张生万,张有贤,申晓红.薄层色谱扫描法同时测定增效联磺片中三组分含量的研究[J].色谱,1994,12(5):364-366. |
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| 作者姓名： | 冯彦琳 张生万 张有贤 申晓红 |
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| 作者单位： | 山西大学化学系 |
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| 基金项目： | 山西省自然科学基金资助项目 |
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| 摘 要： | 提出了增效联磺片中磺胺甲基异唑（ＳＭＺ）、磺胺嘧啶（ＳＤ）及甲氧节胺嘧啶（ＴＭＰ）三组分薄层色谱同时测定的新方法。该法以水饱和的乙酸乙酯－氯仿（２：１）的混合溶剂为展开剂，在硅胶ＧＦ＿（２５４）板上将被测各组分分离后，直接进行薄层色谱扫描测定，操作简便、快速，灵敏度高，重现性好。
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| 关 键 词： | 薄层色谱 磺胺甲基异唑 磺胺嘧啶 甲氧苄胺嘧啶 增效片剂 成分分析. |
Simultaneous Determination of Three Components of Trimethoprim-Sulfadiazine-Sulfamethoxazole Tablets by Thin-Layer Chromatography Scanning |
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| Feng Yanling, Zhang Shengwan, Zhang Youxian and Shen Xiaohong.Simultaneous Determination of Three Components of Trimethoprim-Sulfadiazine-Sulfamethoxazole Tablets by Thin-Layer Chromatography Scanning[J].Chinese Journal of Chromatography,1994,12(5):364-366. |
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| Authors: | Feng Yanling Zhang Shengwan Zhang Youxian and Shen Xiaohong |
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| Abstract: | A new thin-layer chromatographic scanning method was established for the simultaneous determinationof three components of trimethoprim(TMP)-sulfadiazine(SD)-sulfamethoxazole(SMZ)tablets afterdevelopment with 33%chloroform in water saturated ethyl acetate as a developing solvent on silica GF_(254)plate. The method is simple,rapid,sensitive and reproducible. |
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| Keywords: | hin-layer chromatography trimethoprim sulfadiazine sulfamethoxazole synergist tablet components analysis |
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