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液相色谱-质谱联用在兴奋剂检测中的应用及进展
引用本文:秦旸,徐友宣,杨树民,朱绍棠.液相色谱-质谱联用在兴奋剂检测中的应用及进展[J].色谱,2008,26(4):431-436.
作者姓名:秦旸  徐友宣  杨树民  朱绍棠
作者单位:hina Anti-Doping Agency, Beijing 100029, China
摘    要:液相色谱-质谱联用技术已越来越广泛地应用在兴奋剂的检测中,其中包括对各类小分子兴奋剂和肽类激素等的检测。本文综述了近年来液相色谱-质谱联用在兴奋剂检测中的筛选、确证和定量方面的应用及进展情况,并讨论了相关的检测标准。

关 键 词:液相色谱-质谱  兴奋剂检测  综述
收稿时间:2008-6-24
修稿时间:2008-7-30

Applications and progresses of liquid chromatography-mass spectrometry in doping control
QIN Yang,XU Youxuan,YANG Shumin,ZHU Shaotang.Applications and progresses of liquid chromatography-mass spectrometry in doping control[J].Chinese Journal of Chromatography,2008,26(4):431-436.
Authors:QIN Yang  XU Youxuan  YANG Shumin  ZHU Shaotang
Institution:hina Anti-Doping Agency, Beijing 100029, China
Abstract:High performance liquid chromatography-mass spectrometry (LC-MS) has enabled the determination of most of the prohibited drugs in doping analysis, including many small molecular doping agents and peptide hormones. This paper reviews liquid chromatography-mass spectrometry for the screening, identification and quantification of doping agents in urine and other biological samples. Criteria for the identification of compounds by LC-MS are also discussed.
Keywords:liquid chromatography-mass spectrometry (LC-MS)  doping detection  review
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