烟碱样品前处理及分析方法研究进展

烟碱是评价烟草及其制品的感官品质及内在质量的重要指标，同时也是监测食品、环境及人体中尼古丁暴露程度的关键因素。烟碱所在基质复杂，样品多样，针对不同检测环境及要求选择合适高效的分析方法对成功测定烟碱含量至关重要。该文介绍了测定烟草及生物样品中烟碱含量的样品前处理技术（固相/液相微萃取技术和分子印迹法）和常用的检测方法（分光光度法、液相色谱法、气相色谱法、毛细管电泳法、电化学法），评述了每种方法的适用范围、应用实例和研究进展，并讨论了各种检测方法的灵敏度、准确性和检测效率等。

Advances in nicotine pretreatment and determination method

Nicotine is an important indicator in the quality evaluation of tobacco and its related products. Moreover, it is essential to monitor nicotine presence in the environment, food, and human organs. Therefore, the development of a suitable and efficient determination method is crucial to precisely detect nicotine in various samples and complicated matrices. This article reviews the methods of sample preparation (molecular imprinting technology and solid phase/liquid phase microextraction) and methods for nicotine analysis, such as spectrophotometry, liquid chromatography, gas chromatography, capillary electrophoresis, and electrochemical methods, reported in recent years. The advancement in the applications and scopes of these methods are discussed. Furthermore, the sensitivity, accuracy, and detection efficiency of these methods are elaborated on the basis of the reported nicotine determination methods.