Asymmetric Reduction of Ketones Using In Situ Generated Oxazaborolidines From (1R-Camphor as Catalysts |
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| Authors: | V Santhi J Madhusudana Rao |
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| Institution: | 1. Organic Chemistry Division , Regional Research Laboratory [CSIR] , Trivandrum, India, 695019;2. Natural products laboratory, Indian Institute of Chemical Technology [CSIR] , Hyderabad, 500007, India |
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| Abstract: | Benzyl and 1-naphthyl derivatives of 1,2-amino alcohols derived from (1R)-(+)-camphor were made by a simple and efficient procedure and these were used for the generation of oxazaborolidines with borane. The asymmetric reductions of prochiral ketones were carried out using these in situ generated oxazaborolidines as catalysts. |
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