Approaches to the Synthesis of Gibberellic Acid. Construction of the B,C and D Ring System |
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| Authors: | R Bryan Miller |
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| Institution: | Department of Chemistry , Columbia University , New York, New York, 10027 |
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| Abstract: | One of the most challenging aspects of the synthesis of gibberellic acid2 and structurally related compounds such as steviol3 is the construction of the bicyclo3.2.1]octane system with the unusual features of an exocyclic methylene group adjacent to a bridgehead tertiary hydroxyl group. In gibberellic acid this structural feature comprises the C, D ring system, which is fused to the five-membered B ring. |
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