Facile Synthesis of Coumarinyl Isothiocyanate from Amino Coumarin |
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| Authors: | Sagar A Mayekar Atul C Chaskar |
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| Institution: | Department of Chemistry , Institute of Science , Mumbai , India |
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| Abstract: | One-pot conversion of amino coumarin to corresponding coumarinyl isothiocyanate using carbon disulfide, iodine, and pyridine is described. In this reaction, pyridine acts as a solvent as well as a catalyst to give coumarinyl isothiocyanate. Excellent yield, short reaction time, and mild reaction conditions make this method a useful synthetic procedure for one-pot preparation of coumarinyl isothiocyanate. |
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| Keywords: | Amino coumarin coumarinyl isothiocyanate iodine pyridine pyridinium hydroiodide |
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