Microwave-Assisted Method for Synthesis of 1,3-Disubstituted Pyrroles |
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| Authors: | Viera Poláčková Eva Veverková Dariusz Bogdal |
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| Institution: | 1. Faculty of Natural Sciences , Department of Organic Chemistry, Comenius University , Bratislava, Slovak Republic;2. Department of Chemistry and Technology , Politechnika Krakowska , Krakow, Poland |
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| Abstract: | 1,3-Disubstituted pyrroles were prepared by a microwave-assisted reaction of pyrrolidine and aldehydes in toluene as well as in solvent-free conditions. Reactions were completed in a few minutes in the solvent-free condition but a long time (up to 30 min) was necessary to complete reactions in toluene. Yields of products depended considerably on the aldehyde used. |
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| Keywords: | Microwave assisted pyrroles solvent free |
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