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Highly meso-Diastereoselective Pinacol Coupling of Aromatic Aldehydes Mediated by Al Powder/Copper Sulfate in Water |
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| Authors: | Yoshiharu Mitoma Iwao Hashimoto Masashi Tashiro Naoyoshi Egashira |
| Institution: | 1. Department of Bioresource Development , School of Bioresources, Hiroshima Prefectural University , Shobara, Hiroshima, Japan;2. Department of Industrial Chemistry , Wakayama National College of Technology , Gobo City, Japan;3. National Institute of Advanced Science and Technology (AIST) , Tsukuba, Ibaraki, Japan |
| Abstract: | Pinacol-type coupling reaction products presenting a high meso-diastereoselectivity (the ratio dl/meso was 4/96 up to 1/99) were obtained in fair to good yields (24–69%) using several aromatic aldehydes as starting materials and aluminium powder/copper sulfate as catalysts, in water, under reflux conditions. |
| Keywords: | Aqueous media meso-diastereoselectivity reductive coupling |