Green and highly efficient synthesis of pyranopyrazoles in choline chloride/urea deep eutectic solvent

A simple and efficient multicomponent protocol, using ammonium deep eutectic solvent as a dual catalyst and environmentally benign reaction medium, is developed for the synthesis of dihydropyrano2,3-c]pyrazole derivatives. This operationally simple protocol does not involve tedious workup or purification, affording the target compounds in short reaction times and excellent yields and avoiding the use of environmentally hazardous solvents and catalysts.