Choline chloride as an efficient catalyst for the synthesis of styryl-pyrazoles |
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| Authors: | Hardesh K Maurya Kripa Shankar Nainawat |
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| Institution: | Medicinal Chemistry Department, CSIR–Central Institute of Medicinal and Aromatic Plants, Lucknow, India |
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| Abstract: | An efficient and green methodology for syntheses of various styryl-pyrazoles (3) from the reaction of 2-(5-phenyl-1H-pyrazol-3-yl)acetonitriles (1) with substituted benzaldehydes (2) by the use of biodegradable, nonhazardous, naturally occurring, and inexpensive choline chloride and NaOH under an environmentally benign medium has been described. |
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| Keywords: | C?C coupling choline chloride pyrazole styryl-pyrazole |
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