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Metal-free and base-free decarboxylation of substituted cinnamic acids in a deep eutectic solvent |
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| Authors: | Wen-Bing Sheng Yasmin Sumera Chen Chen Ming Zhang Yuxin Lei |
| Institution: | 1. TCM and Ethnomedicine Innovation &2. Development International Laboratory, Academician Atta-ur-Rahman Belt and Road Traditional Medicine Research Center, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, PR China;3. HEJ, Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan |
| Abstract: | AbstractA metal-free and base-free strategy was developed in DES to synthesize styrenes for the first time by decarboxylation of cinnamic acid derivatives, which provided a renewable and cost efficiently protocol to access various styrenes including those with functional groups such as 4-vinylphenol and 1-chloro-4-vinylbenzene. |
| Keywords: | Base-free decarboxylation deep eutectic solvent metal-free substituted styrene |