Modified and environmentally friendly oxidation of phosphorane ylides to vicinal tricarbonyls using unsupported moist Oxone in dichloromethane |
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| Authors: | Kieseung Lee Richard S Lee Joanne S Lee |
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| Institution: | 1. Department of Applied Chemistry &2. Department of Pharmaceutical Engineering, Woosuk University, Chonbuk, Republic of Korea;3. kslee@woosuk.ac.kr;5. School of Pharmacy, University of Southern California, Los Angeles, CA, USA;6. School of Pharmacy, University of the Pacific, Stockton, CA, USA |
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| Abstract: | AbstractModified and eco-friendly oxidation of phosphorane ylides to the corresponding vicinal tricarbonyls (VTC) using unsupported moist Oxone in dichloromethane at room temperature is described. This green oxidation protocol is simple, mild, and highly efficient to operate, and allowing a chemoselective preparation of VTC from various phosphorane ylides without tedious workup procedures of extraction/drying process in excellent yields. |
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| Keywords: | Surface-mediated reaction unsupported moist Oxone phosphorane ylide vicinal tricarbonyl |
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