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Selective Reductions of 1-(Carbonyl)Substituted 2-Nitro-Imidazoles with Alkali Metal Borohydrides and with Borane. Tetrahydrofuran |
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| Authors: | Michael D Threadgill Paul Webb |
| Institution: | Medical Research Council Radiobiology Unit , Chilton, Didcot, Oxfordshire, OX11 0RD |
| Abstract: | Sodium borohydride, lithium borohydride and borane. THF reduce carbonyl groups (esters, amide) in 1-substituted 2-nitroimidazoIes in high yield without reduction of the nitroheterocycle. |
| Keywords: | |