Cyclisation of 4-[2-Cyclofentenyl]-3-Hydroxy [1] Benzopypan-2-One |
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Authors: | K C Hajumdar P K Choudhury |
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Institution: | Department of Chemistry , University of Kalyani , Kalyani , 741235 , WB , India |
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Abstract: | 4-2-cyclopentenyl]-3-hydroxy 1] bonzopyran-2-one(3) was cyclised to the bicyclie coumar in-1,3-ethano-2-bromo-1,2-dihydro-3H-pyrano 2,3-c] 1] benzopyran-5-one (6) by a sequence of reactions viz. acetylation of 3, addition of bromine to cyclopenteny double bond and treating the resulting acetyldibromo compound (5) with 4% alcoholic KOH, Cyclisation of compound (3) with mercuric acetate in methanol gave condensed furan derivative 7 which on reductive demercuration with zinc borohydride in dimethoxyethane gave the 1,3-propano-1,2-dihydrofuro 2,3-c] 1] benzopyran-4-one, 8. Cyclisation of compound 2 with come. H2SO4 furnished a mixture of bicyclic derivative 9 ad furo coumarin derivative 8. |
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