A Convenient Method of Benzylic Oxidation with Pyridinium Chlorochromate |
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| Authors: | Rajendra Rathore Nishi Saxena S Chandrasekaran |
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| Institution: | Department of Chemistry , Indian Institute of Technology , Kanpur, 208016, India |
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| Abstract: | Oxidation of indans and tetralin derivatives to their corresponding indanones and tetralones is of considerable value i n organic synthesis and many methods have been reported for accomplishing this conversion. Traditionally these oxidations are performed with chromic acid in acetic acid and the yields in general are moderate. Recently Eisenbraun4 has studied indetail the benzylic oxidation with the Jones reagent and compared the selectivity and yield of oxidation with other chromium(V1) reagents like bipyridinim chlorochrmate, (BiPCC). It was found that there was no improvement in yield and in the case of BiPCC a molar ratio 16% 1 (oxidant: substrate) was employed to get |
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