| 从猪去氧胆酸甲酯表观合成角鲨多胺 |
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| 引用本文： | 沈季铭,周向东,周维善.从猪去氧胆酸甲酯表观合成角鲨多胺[J].化学学报,2006,64(14):1513-1516. |
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| 作者姓名： | 沈季铭 周向东 周维善 |
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| 作者单位： | 中国科学院上海有机化学研究所,上海,200032 |
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| 摘 要： | 以猪去氧胆酸甲酯为原料, 经15步反应以总产率5.6%表观合成具有抗菌、抗癌活性的海洋甾体角鲨多胺.
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| 关 键 词： | 角鲨多胺 猪去氧胆酸甲酯 表观合成 |
| 收稿时间： | 11 24 2005 12:00AM |
| 修稿时间： | 2005-11-242006-03-24 |
Formal Synthesis of Squalamine from Methylhyodeoxycholanate |
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| SHEN,Ji-Ming,ZHOU,Xiang-Dong,ZHOU,Wei-Shan.Formal Synthesis of Squalamine from Methylhyodeoxycholanate[J].Acta Chimica Sinica,2006,64(14):1513-1516. |
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| Authors: | SHEN Ji-Ming ZHOU Xiang-Dong ZHOU Wei-Shan |
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| Institution: | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032 |
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| Abstract: | A marine steroid squalamine with antibacteria and antitumor activity was formally synthesized in 15 steps with 5.6% overall yield from methylhyodeoxycholanate. |
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| Keywords: | squalamine methylhyodeoxycholanate formal synthesis |
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