（焦）脱镁叶绿酸－a甲酯的N~(21)N~(23)轴向化学结构修饰及其对可见光吸收的影响

以脱镁叶绿酸－a甲酯和焦脱镁叶绿酸-a甲酯为起始原料，通过3－位乙烯基和 13~1-位环上基的化学反应，改变二氢中卟吩母环上N~(21)-N~(23)轴向的化学结构 ，完成了（焦）脱镁叶绿酸－a甲酯衍生物2～15的合成，并对其可见光谱的变化进 行了讨论。所合成的新叶绿酸衍生物均经UV，IR，~1H NMR及元素分析证明其结构 。

Chemical Modifications along N~(21)-N~(23) Axis in Methyl (Pyro) pheophorbide-a and Effect on the Visible Spectra

Methyl pheophorbide a and pyropheophorbide a were used as starting material for the synthesis of new chlorin compounds. The modifications of chemical structure along N 21 N 23 axis were focused on the vinyl group at 3 position and the carbonyl group at 13 1 position. A series of pheophorbide and pyropheophorbide derivatives were synthesized and effect on their visible spectra was discussed. The structures of all new compounds were characterized by elemental analysis, UV, IR and 1H NMR spectra.