| 新一代生物医用材料 |
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| 引用本文： | 刘盛辉,郎美东.新一代生物医用材料[J].高分子通报,2005,14(6):113-117,128. |
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| 作者姓名： | 刘盛辉 郎美东 |
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| 作者单位： | 浙江工业大学,化学工程与材料学院,杭州,310014;华东理工大学,材料科学与工程学院,上海,200237 |
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| 基金项目： | 国家自然科学基金资助项目20374013;教育部留学回国人员科研启动基金资助项目、上海市科学技术委员会基础研究重点资助项目（03JC14023）;上海市重点学科建设项目; |
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| 摘 要： | 第一代生物医用材料是生物相容和生物惰性材料；第二代生物医用材料是生物活性或可生物降解吸收材料；第三代生物医用材料是同时具有生物活性和生物降解性的新一代生物医用材料。作为细胞外基质，它们可在分子水平上激活基因、刺激细胞增殖、诱导其组织分化进而构筑成新的组织和器官。
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| 关 键 词： | 第三代生物医用材料 组织工程 细胞和基因活化 细胞外基质 生物活性 |
New-generation Biomedical Materials |
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| LIU Sheng-hui,LANG Mei-dong.New-generation Biomedical Materials[J].Polymer Bulletin,2005,14(6):113-117,128. |
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| Authors: | LIU Sheng-hui LANG Mei-dong |
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| Institution: | 1. College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou 310014, China; 2. School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China |
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| Abstract: | First-generation biomedical materials were biocompatible and bioinert materials. Second-generation biomaterials were designed to be either resorbable or bioactive. Third-generation biomaterials are combining these two properties. These new generation biomaterials are designed as the extracellular matrix to activate genes and elicit the specific interactions with cell, and thereby to direct cell proliferation, differentiation, organization, and last to repair or regenerate the living tissues and organs. |
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| Keywords: | Third-generation biomedical materials Tissue engineering Cell and gene-activation Extracellular matrix Bioactivity |
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