反相高效液相色谱法测定高能发射药中5种组分

提出了反相高效液相色谱法测定高能发射药中5种组分硝化甘油(NG)、黑索今(RDX)、硝基胍(NQ)、Ⅱ号中定剂(C2)和邻苯二甲酸二正辛酯(DOP)的含量。试样溶解后进行色谱分离,采用Agilent色谱柱(150mm×4.6mm,5μm),流动相为甲醇-水(60+40)混合溶液(用于分离NG、RDX、NQ和C2)和甲醇-水(95+5)混合溶液(用于分离DOP),在波长220nm处进行测定。NG的质量浓度在0.42～4.08g.L-1,RDX在1.41～5.04g.L-1,NQ在1.11～3.74g.L-1,C2在0.07～0.90g.L-1,DOP在0.08～0.37g.L-1时分别与其峰面积呈线性关系。5种化合物的加标回收率在99.3%～101.9%之间;相对标准偏差(n=6)在0.19%～3.1%之间。

RP-HPLC Determination of 5 Components in High Energy Gun Propellant

RP-HPLC was applied to the determination of 5 components,including nitro-glycerol(NG),hexogen(RDX),nitroguanidine(NQ),centralite Ⅱ(C2) and dioctyl o-phthalate(DOP) in high energy gun propellant.The sample after dissolution was separated by using Agilent column(150 mm×4.6 mm,5 μm) as stationary phase,and a mixture of CH3OH-H2O(60+40) as mobile phase for NG,RDX,NQ and C2,and mixture of CH3OH-H2O(95+5) as mobile phase for DOP.The contents of the 5 components were determined at the wavelength 220 nm.Linear relationships between values of peak area and mass concentration of NG,RDX,NQ,C2 and DOP were kept in ranges of 0.42-4.08 g·L-1,1.41-5.04 g·L-1,1.11-3.74 g·L-1,0.07-0.90 g·L-1,0.08-0.37 g·L-1,respectively.Tests for recovery and precision were made by standard addition method.Values of recovery and RSD′s(n=6) found were in the range of 99.3%-101.9% and 0.19%-3.1%,respectively.