A new epidioxy-tetracyclic triterpenoid from Poria cocos Wolf |
| |
| Authors: | Shiping Li Zhixin Wang Rui Gu Yiwu Zhao Wenzhe Huang Zhenzhong Wang |
| |
| Institution: | 1. Jiangsu Kanion Pharmaceutical Co. Ltd., Lianyungang, People’s Republic of China;2. State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process, Lianyungang, People’s Republic of China;3. Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, People’s Republic of China |
| |
| Abstract: | A new epidioxy-tetracyclic triterpenoid, 3-(2-hydroxyacetoxy)-5α, 8α-peroxydehydrotumulosic acid (10), along with nine known compounds were isolated from Poria cocos Wolf (Polyporaceae). Their structures were determined by extensive spectroscopic analyses and comparison with literature data. The cytotoxicity of these compounds against human cancer cell lines MNK-45 was evaluated by MTT method. |
| |
| Keywords: | Poria cocos Wolf Polyporaceae epidioxy-tetracyclic triterpenoid cytotoxicity |
|
|
