Two new dammarane-type triterpene sapogenins from Chinese red ginseng |
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Authors: | Qian Zheng Zhuo Li Jinping Liu Liu Han Nanqi Zhang Hao Zhang |
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Institution: | College of Pharmacy, Jilin University, 126 Xinmin Street, Chaoyang District, Changchun, Jilin CN 130021, P.R. China |
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Abstract: | Two new dammarane-type triterpene sapogenins were isolated from the Chinese red ginseng. The new sapogenins were named as 24,26-dihydroxy-panaxdiol (1) and 24-hydroxy-panaxdiol (2). Their structures were elucidated by the combined analysis of NMR and mass spectrometry as 20(S),25(R)-epoxydammarane-3β,12β,24β,26-tetraol (1) and 20(S),25-epoxydammarane-3β,12β,24α-triol (2). The complete signal assignments of the two compounds were carried out by 2D NMR spectral and NOE differential spectroscopy analysis. |
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Keywords: | dammarane-type triterpene sapogenin Chinese red ginseng 20(S) 25(R)-epoxydammarane-3β 12β 24β 26-tetraol 20(S) 25-epoxydammarane-3β 12β 24α-triol |
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