Diarylheptanoids from the fresh pericarps of Juglans sigillata |
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| Authors: | Jingjing Liang Xiaogang Peng Jia Zhou Ming Zhou |
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| Institution: | Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, People’s Republic of China |
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| Abstract: | One new diarylheptanoid (3S)-3′, 4″-epoxy-1-(4′-hydroxylphenyl)-7-(3″-hydroxylphenyl) heptane-3-hydroxy (1), together with eleven known ones (2–12), was isolated from the fresh pericarps of Juglans sigillata. Their structures were elucidated on the basis of extensive spectroscopic methods, including HR-ESI-MS, 1D and 2D-NMR. All isolates were evaluated for their cytotoxic activities in vitro against the growth of human cancer cells lines HT-29 and MCF-7 by MTT assay. |
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| Keywords: | Juglans sigillata Juglandaceae fresh pericarps diarylheptanoids |
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