Antitumour activity of Prosopis cineraria (L.) Druce against Ehrlich ascites carcinoma-induced mice |
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Authors: | Robertson Stellaa Narayanan N Raj Kapoor B |
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Institution: | Department of Pharmacognosy, Maharaji College of Pharmacy, Chennai 600090, Tamil Nadu, India. uystella_mpharm@yahoo.co.in |
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Abstract: | The antitumour activity of the hydroalcoholic extract of the leaf (PCL) and stem bark (PCB) of Prosopis cineraria (L.) in Swiss albino mice was evaluated against an Ehrlich ascites carcinoma (EAC) tumour model. The activity was assessed using survival time, peritoneal cells, haematological studies, lipid peroxidation, antioxidant enzymes such as superoxide dismutase, catalase, glutathione peroxidase, glutathione S-transferase, solid tumour mass and in?vitro cytotoxicity. PCL and PCB were found to be potent and possessed significant cytotoxicity towards EAC tumour cells. |
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