A new aliphatic ester of hydroxysalicylic acid from fermented Carica papaya L. preparation with a potential hair growth stimulating activity |
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| Authors: | Ahmed Ashour Yhiya Amen Toshinori Nakagawa Yasuharu Niwa Amira Mira Koichiro Ohnuki |
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| Institution: | 1. Division of Systematic Forest and Forest Products Sciences, Department of Agro-Environmental Sciences, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Fukuoka, Japan;2. Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt;3. Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt;4. Department of Biological and Environmental Chemistry, Kinki University, Fukuoka, Japan |
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| Abstract: | AbstractAn aliphatic ester of hydroxysalicylic acid (6), reported for the first time from a natural source in addition to five known compounds were isolated from the fermented Carica papaya L. preparation, a commercialized functional food. The known compounds were identified as 5-hydroxymethylfurfuraldehyde (1), trans-caffeic acid (2), butyl 4-hydroxybenzoate (butylparaben) (3), lycopene (4), benzyl isothiocyanate (5). Compounds 1 and 3 were reported for the first time from Papaya fruits through this study. The new compound showed a moderate antioxidant activity and a potent hair growth stimulating activity in vitro. |
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| Keywords: | Carica papaya L fermented preparation anti-oxidant hair growth |
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