A new dimeric alkylresorcinol from the stem barks of Swintonia floribunda (Anacardiaceae) |
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| Authors: | Phu H Dang Linh T T Nguyen Hue T T Nguyen Tho H Le Truong N V Do Hai X Nguyen |
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| Institution: | Faculty of Chemistry, VNUHCM–University of Science, Ho Chi Minh City, Vietnam |
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| Abstract: | From an EtOAc-soluble fraction of the stem barks of Swintonia floribunda (Anacardiaceae), one new dimeric alkylresorcinol named integracin E (1), together with 4 known compounds (2–5) were isolated. Their chemical structures were elucidated based on the spectroscopic data interpretation. The absolute configuration of 1 was determined by the specific rotation analysis of its acid-catalyzed hydrolysis product. Compound 1 showed potent tyrosinase inhibitory activity with an IC50 value of 48.2?μM. |
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| Keywords: | Swintonia floribunda Anacardiaceae alkylresorcinol tyrosinase inhibitory |
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