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Review: Separation and Pharmacology of Chiral Compounds in Traditional Chinese Medicine
Authors:Xiong-Fei Wang  Ke Sun  Yue-Zhu Ding
Institution:School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China
Abstract:More than 60% commonly used pharmaceutical active ingredients are chiral compounds. Developing more effective and safe chiral compounds has become a focus in the pharmaceutical industry. Chiral compounds widely exist in traditional Chinese medicine and include alkaloids, flavonoids, volatile oils, and amino acids. The characterization of chiral compounds used in traditional Chinese medicine remains limited. Here, the characterization of chiral compounds commonly used in traditional Chinese medicine is reviewed focusing upon their separation and pharmacology.
Keywords:Chiral compound  chiral separation  high-performance liquid chromatography  pharmacology  traditional Chinese medicine
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