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Electrochemical Detection of Epinephrine Using an L-Glutamic Acid Functionalized Graphene Modified Electrode
Abstract:The development and application of an L-glutamic acid functionalized graphene nanocomposite, modified glassy carbon electrode are reported for the determination of epinephrine. The properties of the nanocomposite were characterized by scanning electron microscopy, ultraviolet-visible absorption spectroscopy, infrared spectroscopy, cyclic voltammetry, and electrochemical impedance spectroscopy. The modified electrode had high sensitivity and strongly catalytic activity for the detection of epinephrine. A linear relationship between the epinephrine concentration and the current response was obtained in the range of 1 × 10?7 M to 1 × 10?3 M by differential pulse voltammetry with a limit of detection of 3 × 10?8 M. The modified electrode was employed to determine epinephrine in urine with satisfactory results.
Keywords:Electrochemical sensor  Epinephrine  Graphene  L-glutamic acid  Nanocomposite
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