Design of sodium lanthanide fluoride nanocrystals for NIR imaging and targeted therapy |
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| Institution: | 1. Institute of Biomedical Materials and Engineering, College of Materials Science and Engineering, College of Chemistry and Chemical Engineering, Qingdao University, Qingdao, 266071, China;2. State Key Laboratory of Bio-Fibers and Eco-Textiles, Qingdao University, Qingdao, 266071, China;3. Key Laboratory of Biomass Chemical Engineering of Ministry of Education, Center for Bionanoengineering, And Department of Chemical and Biological Engineering, Zhejiang University, Hangzhou, Zhejiang, 310027, China;4. School of Materials Science and Engineering, Shandong University of Technology, Zibo, 255000, China |
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| Abstract: | Since the 18th century, rare-earth ions have been widely used as active dopants in inorganic lattices due to their unique optical properties. Rare-earth doping can control the crystal phase, morphology and size of nanomaterials, resulting in adjustable optical response of doped nanomaterials. The substrate of nanostructures can greatly affect the physical and chemical behavior of rare-earth ions. Therefore, it is also important to find suitable host materials. Among various new host materials, sodium lanthanide fluoride (NaLnF4) nanoparticles are known for their photoluminescence properties and stability. This paper emphasizes the latest progress of NaLnF4 and its derivatives nanoparticles and their related applications in various biological fields. This review covers the key criteria of NaLnF4 and its derivatives, including basic electronic structure, lattice environment, doping strategy, surface functionalization and basic design principles for biological applications. At the same time, this paper also discusses the obstacles encountered in the development process and the research directions and challenges of future new applications. |
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| Keywords: | Rare-earth doping Photoluminescence properties Biological applications |
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