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Structure and Biological Activities of 2-( 1,3-Dithiolan-2-ylidene)-1-phenyl-2- ( 1,2,4-triazol-1 -yl ) ethanone
作者姓名:XU  Liang-zhong  LI  Wei-hua  YU  Guan-ping  QIN  Yong-qi  YANG  Shuang-hua  HOU  Bao-rong
作者单位:[1]College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China [2]College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266033, P. R. China [3]Institute of Oceanology, Chinese Academy of Sciences, Qingdno 266071, P. R. China
摘    要:In order to find leading compounds with an excellent fungicidal activity, the title compound 2-( 1,3-dithiolan-2- yl-idene)-1-phenyl-2-( 1,2,4-tfiazol-1-yl) ethanone was synthesized according to the biological isosterism and its structure was confirmed by means of IR, MS, ^1 H NMR and elemental analysis. The single crystal structure of the title compound was determined by X-ray diffraction. The preliminary biological test shows that the synthesized compound exhibits some biological activities.

关 键 词:三唑  二硫杂环戊烷  水晶结构  生物活性
文章编号:1005-9040(2005)-05-528-03
收稿时间:2004-09-29

Structure and Biological Activities of 2-(1,3-Dithiolan-2-ylidene)-1-phenyl-2-(1,2,4-triazol-1-yl)ethanone
XU Liang-zhong LI Wei-hua YU Guan-ping QIN Yong-qi YANG Shuang-hua HOU Bao-rong.Structure and Biological Activities of 2-(1,3-Dithiolan-2-ylidene)-1-phenyl-2-(1,2,4-triazol-1-yl)ethanone[J].Chemical Research in Chinese University,2005,21(5):528-530.
Authors:XU Liang-zhong  LI Wei-hua  YU Guan-ping  QIN Yong-qi  YANG Shuang-hua  HOU Bao-rong
Institution:1. College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China;
2. College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266033, P. R. China;
3. Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, P. R. China
Abstract:In order to find leading compounds with an excellent fungicidal activity, the title compound 2-(1,3-dithiolan-2-yl-idene)-1-phenyl-2-(1,2,4-triazol-1-yl)ethanone was synthesized according to the biological isosterism and its stru-cture was confirmed by means of IR, MS, 1H NMR and elemental analysis. The single crystal structure of the title compound was determined by X-ray diffraction. The preliminary biological test shows that the synthesized compound exhibits some biological activities.
Keywords:1H-1  2  4-Triazole  1  3-Dithiolan  Crystal structure  Biological activity
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