油脂降解培养基优化的遗传算法实验研究 |
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引用本文: | 李绍新,邢达,秦华明,杨湘波,谭石慈.油脂降解培养基优化的遗传算法实验研究[J].分析化学,2004,32(4):481-484. |
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作者姓名: | 李绍新 邢达 秦华明 杨湘波 谭石慈 |
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作者单位: | 华南师范大学激光生命科学研究所,广州,510631;华南理工大学生物工程系,广州,510631 |
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基金项目: | 广东省自然科学基金资助项目 (No .0 15 0 12 ) |
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摘 要: | 我们运用遗传算法,首次对利用热带假丝酵母降解油脂的培养基优化问题进行了研究。通过5代实验完成了50个实验样本、6种培养基成分、64个浓度水平的优化任务。按照优化后的培养基组成,热带假丝酵母降解油脂的降解率为95.4%,比正交设计法提高了7.63%。实验结果表明:利用遗传算法可优化培养基成分含量,取得更好的效果;遗传算法是一种优于单因素试验法和正交设计法的新型、高效的培养基优化方法。
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关 键 词: | 油脂降解 培养基优化 遗传算法 |
Experimental Study on Genetic Algorithms of Medium Optimization for Oil-degradation |
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Abstract: | Medium optimization of the culture for oil degradation by Candida tropicalis using genetic algorithms (GA) was studied. The 64 concentration levels of 6 medium components were optimized within 50 experiments. The results show that GA can be applied in the medium optimization and better results are obtained. Employing optimized medium composition, a final oil degradation rate of 95.4% was obtained and it was improved by 6.94% compared to the results with the medium before optimization. GA is an efficient new medium optimum method which is superior to the other optimum means such as orthogonal array method. |
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Keywords: | Oil degradation medium optimization genetic algorithms |
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