| 丹皮药材的高效液相色谱-质谱/质谱研究 |
| |
| 引用本文： | 梁琼麟,温华珍,王玉莉,罗国安,王义明.丹皮药材的高效液相色谱-质谱/质谱研究[J].分析化学,2005,33(11):1555-1559. |
| |
| 作者姓名： | 梁琼麟 温华珍 王玉莉 罗国安 王义明 |
| |
| 作者单位： | 清华大学化学系,北京100084;清华大学化学系,北京100084;江西中医学院药学系,南昌,330006 |
| |
| 基金项目： | 国家自然科学基金;科技部攻关项目 |
| |
| 摘 要： | 采用高效液相色谱．质谱／质谱建立了丹皮药材的指纹图谱方法。丹皮药材中的主要成分得到较好分离，指纹峰重现性好，通过多维联用技术获得各指纹峰的保留时间、分子量及结构信息，推测出15个指纹峰的可能组成。结果表明：所建立的丹皮指纹图谱信息量丰富，对丹皮药材的化学表征及质量评价有重要的参考价值。
|
| 关 键 词： | 丹皮 高效液相色谱-质谱/质谱 指纹图谱 |
| 收稿时间： | 12 30 2004 12:00AM |
| 修稿时间： | 2004-12-302005-06-21 |
Investigation of Cortex Moutan by Liquid Chromatography Coupling with Tandem Mass Spectrometry |
| |
| Liang Qionglin,Wen Huazhen,Wang Yuli,Luo Guoan,Wang Yiming.Investigation of Cortex Moutan by Liquid Chromatography Coupling with Tandem Mass Spectrometry[J].Chinese Journal of Analytical Chemistry,2005,33(11):1555-1559. |
| |
| Authors: | Liang Qionglin Wen Huazhen Wang Yuli Luo Guoan Wang Yiming |
| |
| Institution: | Department of Chemistry, Tsinghua University, Beijing 100084; Department of Pharmacy, Jiangxi College of Traditional Chinese Medicine, Nanchang 330006 |
| |
| Abstract: | A high performance liquid chromatography tandem mass spectrometric(HPLC/MS/MS) method was developed to establish the fingerprint of Cortex Moutan,a Chinese medicinal herb.The major constituents among Cortex Moutan from different origins were separated well by HPLC and the fingerprint had a good(repeatability).Fifteen peaks in the fingerprint were identified by LC/MS/MS according to their retention time,molecular weight and fragmentation information.The result showed that the presented fingerprint of Cortex Moutan contained plenty of information,which was quite valuable for the quality evaluation as well as chemical characterization of this Chinese herb. |
| |
| Keywords: | Cortex Moutan high performance liquid chromatography tandem mass spectrometric fingerprint |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
