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| 脂组学及其研究进展 | |
| 引用本文： | 朱超,胡坪,梁琼麟,王义明,罗国安.脂组学及其研究进展[J].分析化学,2009,37(9). |
| 作者姓名： | 朱超 胡坪 梁琼麟 王义明 罗国安 |
| 作者单位： | 1. 华东理工大学药学院,上海,200237;清华大学化学系,北京,100084 2. 华东理工大学化学与分子工程学院,上海,200237 3. 清华大学化学系,北京,100084 |
| 基金项目： | 国家自然科学基金项目，国家973项目 |
| 摘 要： | 脂质的生物功能具有多样性,其代谢与多种疾病的发生、发展密切相关.脂质的分析量化对研究疾病发生机理和诊断治疗,以及医药研发有非常重要的生物学意义.分析技术的快速发展,特别是质谱及其联用技术的运用,促使脂质分析不断完善.脂组学就是对生物样本中脂质的整体分析,是代谢组学的重要组成部分,能够促进代谢组学的发展.本文就脂质的生物功能、脂质分析以及脂组学的研究现状作简要评述. |
| 关 键 词： | 脂组学 脂质分析 电喷雾离子化质谱 代谢组学 评述 |
Recent Advances in Lipidomics |
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| ZHU Chao,HU Ping,LIANG Qiong-Lin,WANG Yi-Ming,LUO Guo-An.Recent Advances in Lipidomics[J].Chinese Journal of Analytical Chemistry,2009,37(9). | |
| Authors: | ZHU Chao HU Ping LIANG Qiong-Lin WANG Yi-Ming LUO Guo-An |
| Institution: | ZHU Chao1,2,HU Ping3,LIANG Qiong-Lin2,WANG Yi-Ming2,LUO Guo-An21(School of Pharmacy,East China University of Science and Technology,Shanghai 200237)2(Department of Chemistry,Tsinghua University,Beijing 100084)3(School of Chemistry and Molecular Engineering,Shanghai 200237) |
| Abstract: | Lipids,which have various biological functions,are closely related to the nosogenesis and aggravation of many diseases.Both qualitative and quantitative determinations of lipids have all-important biological significance in disease diagnosis and treatment,as well as in drug research and development.With the development of analytical technique,especially chromatography combined with mass spectrometry,lipid research is being improved more quickly.Lipidomics is a sub-emerging field of metabonomics research,and... |
| Keywords: | Lipidomics lipid analysis electrospray ionization mass spectrometry metabonomics review |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |