| 3-羟基丁酸的气相色谱分析 |
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| 引用本文： | 杨文玲,马沛生,寇登民.3-羟基丁酸的气相色谱分析[J].分析化学,2000,28(9):1161-1164. |
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| 作者姓名： | 杨文玲 马沛生 寇登民 |
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| 作者单位： | 1. 天津大学化工学院,天津,300072
2. 南开大学化学系,天津,300071 |
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| 摘 要： | 采用ＢＦ３－ＣＨ３ＯＨ酯化衍生法，以正辛酸作内标，建立了３－羟基丁酸、巴豆酸、３羟基丁醛、巴豆醛等混合体系中３－羟基丁酸的气相色谱分析方法，利用标准样对照并结合质谱分析确定了化学合成３－羟基丁酸反应混合物的组成。该法线性范围为０．４０～１６０．６７ｇ／Ｌ，相关系数为ｒ＝０．９９９５。方法快速、简单、重现性好，并用于化学合成３－羟基丁酸反应混合物的分析，结果令人满意。
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| 关 键 词： | 3－羟基丁酸 气相色谱法 甲酯衍生物 分析 |
Gas Chromatographic Analysis of 3-Hydroxybutyric Acid |
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| Yang Wenling,Ma Peisheng,Kou Dengmin.Gas Chromatographic Analysis of 3-Hydroxybutyric Acid[J].Chinese Journal of Analytical Chemistry,2000,28(9):1161-1164. |
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| Authors: | Yang Wenling Ma Peisheng Kou Dengmin |
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| Abstract: | A method has been developed for the separation and determination of 3-bydroxybutyric acid in mixtures of 3-hydroxybutyric acid,3-hydroxybutanal, crotonic acid,Crotonaldehyde and organic solvents by capillary gas chromatography using the methyl ester derivatives and n-octanoic acid as internal standard. The composition of reaction mixtures in chemical synthesis of 3-hydroxybutyric acid was determined by comparing with the standard compounds and mass spectrometirc analysis. The quantitative analysis of 3-hydroxybutyric acid was done by internal standard method. The calibration curve was linear over the range from 0.40 g/L to 160. 67 g/L with a correlation coefficient of 0. 9995. The method is rapid, simple and good of repeatability, and it has been applied to the determination of reaction mixtures in chemical synthesis of 3-hydroxybutyric acid with satisfactory results. |
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| Keywords: | 3-Hydroxybrutric acid gas chromatography methyl ester derivative |
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