| 纳米级造影剂在肿瘤影像学诊疗中的基础应用进展 |
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| 引用本文： | 朱小琪,刘军杰,李红学,周知展.纳米级造影剂在肿瘤影像学诊疗中的基础应用进展[J].影像科学与光化学,2021,39(2). |
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| 作者姓名： | 朱小琪 刘军杰 李红学 周知展 |
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| 作者单位： | 广西医科大学附属肿瘤医院超声科,广西南宁530021 |
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| 基金项目： | 广西自然科学基金(2017GXNSFBA198234);桂科项目(AB18221103)资助。 |
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| 摘 要： | 肿瘤的早期诊断对其生存率及预后有极大的意义,医学成像造影剂的应用可极大地提高肿瘤的早期诊断水平。通过新兴纳米技术开发无毒、成像能力更强、循环时间更长的纳米级造影剂是目前研究的热点。本文综述了纳米级造影剂在MRI、CT、US、PET和SPECT等生物医学成像技术中,对于肿瘤诊疗的基础应用,并列举了部分研究实例。纳米级造影剂具有广阔的临床应用前景,未来的研究重点将会是开发集诊断、治疗于一体的多功能的纳米平台。
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| 关 键 词： | 纳米材料 造影剂 影像诊断 肿瘤 |
Advances in Basic Application of Nano-sized Contrast Agents to Imaging Diagnosis of Tumors |
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| ZHU Xiaoqi,LIU Junjie,LI Hongxue,ZHOU Zhizhan.Advances in Basic Application of Nano-sized Contrast Agents to Imaging Diagnosis of Tumors[J].Imaging Science and Photochemistry,2021,39(2). |
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| Authors: | ZHU Xiaoqi LIU Junjie LI Hongxue ZHOU Zhizhan |
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| Institution: | (Ultrasonic Department,Affiliated Tumor Hospital,Guangxi Medical University,Nanning 530021,Guangxi,P.R.China) |
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| Abstract: | The early diagnosis of tumors,which is crucial to patients’survival rate and prognosis,can be greatly improved by the application of medical imaging contrast agents.The development of non-toxic nano-sized contrast agents with stronger imaging ability and longer cycling time through emerging nanotechnology is a hot topic in current research.Herein,the basic applications of such agents to tumor diagnosis of biomedical imaging technologies such as MRI,CT,US,PET and SPECT are summarized,together with some research examples.The nano-sized contrast agents are confirmed to have broad clinical application prospects.Moreover,the future research direction of developing a multi-functional nano-sized platform integrating diagnosis and treatment is proposed. |
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| Keywords: | nanoparticle contrast agent imaging diagnosis tumor |
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