以尼罗红为探针对新型两亲性树枝形聚合物微环境的研究

本工作合成了一系列外围以三缩四乙二醇单甲醚修饰的烷基芳醚骨架两亲性树枝形聚合物Gn(n=0—3),化合物通过了1H-NMR,IR和MALDI-TOF-MS的表征.利用吸收光谱,稳态和时间分辨荧光光谱研究了水溶液中Gn对尼罗红分子的增溶作用以及Gn内部微环境的极性.研究结果表明,高代数树枝形聚合物Gn对尼罗红具有更好的增溶效果.1—3代树枝形聚合物Gn内部疏水孔腔微环境极性随代数增加而逐渐降低,G1和G2树枝形聚合物具有相似的微环境极性,而由于构象的变化使G3具有更加疏水的微环境.

Investigation of the Microenvironment of Novel Amphiphilic Dendrimers with Nile Red as a Probe

Amphiphilic poly(alkyl aryl ether) dendrimers with tetraethylene glycol monomethyl ether at their periphery(Gn,n=0—3),were synthesized by a convergent growth methodology and their structures were characterized by 1H NMR,IR and mass spectroscopy(MALDI-TOF).The microenvironment of these dendrimers was studied by using Nile Red as a fluorescence probe.The absorption spectra of Nile Red in water and Gn aqueous solutions indicate that the solubility of Nile Red increases dramatically with the increase of dendrimer generation.The steady state and time resolved fluorescence studies reveal that the microenvironment polarity of Gn(n=1—3) decreases with the increase of dendrimer generation.G1 and G2 dendrimers have similar microenvironment polarity,while G3 has a more hydrophobic inner cavity due to its globular structure.