腹部彩超联合CA125诊断卵巢浆液性肿瘤的研究

本研究探讨腹部彩超联合糖类抗原125(CA125)诊断卵巢浆液性肿瘤的价值。选取卵巢浆液性肿瘤患者80例,其中卵巢浆液性囊腺瘤患者23例,浆液性交界性肿瘤患者30例,浆液性癌患者27例,比较各组超声特征及血清CA125差异。浆液性交界性肿瘤、浆液性癌患者囊实性回声、有血流分布、腹水比例明显高于卵巢浆液性囊腺瘤患者(P<0.05),形态规则、边界清晰比例明显低于卵巢浆液性囊腺瘤患者(P<0.05);浆液性癌患者血清CA125为(301.45±104.42)U/mL,明显高于浆液性交界性肿瘤和卵巢浆液性囊腺瘤患者(P<0.05);浆液性交界性肿瘤患者血清CA125为(210.10±98.28)U/mL,明显高于卵巢浆液性囊腺瘤患者(P<0.05);超声联合血清CA125诊断浆液性癌的特异性、准确率和阳性预测值分别为90.57%、87.50%和81.48%,明显高于超声检查(P<0.05)。腹部彩超联合CA125鉴别诊断卵巢浆液性肿瘤有较好的价值。

Study of Abdominal Color Doppler Ultrasound Combined with CA125 in the Diagnosis of Ovarian Serous Tumors

This study discussed the value of abdominal color ultrasound combined with carbohydrate antigen 125(CA125)in the diagnosis of ovarian serous tumors.A total of 80 cases of ovarian serous tumor patient were selected,including 23 cases of ovarian serous cystadenoma,30 cases of serous borderline tumor and 27 cases of serous carcinoma,the differences of ultrasound characteristics and serum CA125 in each group were compared.The proportion of cystic solid echo,blood flow distribution and ascites in patients with serous borderline tumor and serous carcinoma was significantly higher than that in patients with ovarian serous cystadenoma(P<0.05),and the proportion of regular shape and clear boundary was significantly lower than that in patients with ovarian serous cystadenoma(P<0.05).The serum CA125 of serous carcinoma patients was(301.45±104.42)U/mL,which was significantly higher than that in patients with serous borderline tumor and ovarian serous cystadenoma(P<0.05).The serum CA125 of serous borderline tumor patients was(210.10±98.28)U/mL,which was significantly higher than that in patients with ovarian serous cystadenoma(P<0.05).The specificity,accuracy and positive predictive value of ultrasound combined with serum CA125 in the diagnosis of serous carcinoma were 90.57%,87.50%and 81.48%respectively,which were significantly higher than those of ultrasound(P<0.05).Abdominal color Doppler ultrasound combined with CA125 has a good value in differential diagnosis of ovarian serous tumor.