| A型吸附树脂分离纯化杜仲中京尼平甙酸 |
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| 引用本文： | 曹慧,陈晓青,肖建波.A型吸附树脂分离纯化杜仲中京尼平甙酸[J].离子交换与吸附,2005,21(5):415-423. |
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| 作者姓名： | 曹慧 陈晓青 肖建波 |
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| 作者单位： | 1. 中南大学化学化工学院,长沙,410083;南通大学化学化工学院,南通,226000
2. 中南大学化学化工学院,长沙,410083 |
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| 基金项目： | 国家自然科学基金，湖南省科研项目 |
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| 摘 要： | 比较了NKA-9、D311、S-8、HPD600、NKA-2、A型、D140和聚酰胺等8种树脂对杜仲中降血压活性成分京尼平甙酸的吸附及脱附性能,从中筛选出吸附率及脱附率均较高的A型树脂进行试验.确定了最佳工艺条件:杜仲皮粉末用50%乙醇水溶液提取后,95%乙醇沉淀,上清液回收乙醇后,用蒸馏水稀释,调节pH=6～9后用A型树脂吸附,15%乙醇溶液洗脱,流速为1.5ml/min,洗脱液浓缩后冷冻干燥得产品.
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| 关 键 词： | 京尼平甙酸 A型吸附树脂 分离纯化 |
| 文章编号： | 1001-5493(2005)05-0415-09 |
| 收稿时间： | 2004-12-06 |
| 修稿时间： | 2004年12月6日 |
SEPARATION AND PURIFICATION OF GENIPOSIDIC ACID OF EUCOMIA ON A# ADSORPTION RESIN |
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| CAO Hui,CHEN Xiaoqing,XIAO Jianbo.SEPARATION AND PURIFICATION OF GENIPOSIDIC ACID OF EUCOMIA ON A# ADSORPTION RESIN[J].Ion Exchange and Adsorption,2005,21(5):415-423. |
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| Authors: | CAO Hui CHEN Xiaoqing XIAO Jianbo |
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| Institution: | 1 Department of Chemistry and Chemical Engineering Central South University. Changsha 410083, China; 2 Department of Chemistry and Chemical Engineering Nantong University, Nantong 410083, China |
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| Abstract: | Adsorption and desorption characteristic of macroporous adsorption resins NKA-9, D311, S-8, HPD600, NKA-2, A#, and D140 for GPA in Eucommia was investigated and A# resin was chosen for its high adsorption rate (88.17%) and desorption rate (97.71%). The best technology parameters were obtained as following. The bark of Eucommia was extracted with 50% ethanol and the extraction was precipitated by 95% ethanol. After pH of supernatant liquid was regulated to 6~9 the A# resin was used to adsorb GPA for 220 min. Then column chromatograph was used and the elution of 15% ethanol was collected with flowing rate of 1.5ml/min. GPA was obtained by freeze drying. |
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| Keywords: | Adsorption resins Separation and purification Geniposidic acid |
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