Synthesis of some 4-thiazolidone derivatives from 4-(cyclo-3-alkenyl)thiosemicarbazones |
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Authors: | I V Smolanka N P Man'o T A Krasnitskaya |
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Institution: | (1) Uzhgorod State University, 294005 Uzhgorod |
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Abstract: | The reaction of 4-(cyclo-3-pentenyl)- and 4-(cyclo-3-hexenyl) thiosemicarbazones with chloroacetic acid gave 2-hydrazono derivatives of 3-cyclo-pentenyl (cyclohexenyl) thioazolid-4-one, the condensation of which with aromatic aldehydes gave 5-benzylidene derivatives. Representatives of 4-thiazolidone with a carboxy group in the 5 position were synthesized by condensation of the same thiosemicarbazones with maleic anhydride. Some of the substances obtained have bactericidal activity.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 627–628, May, 1981. |
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