| 邻氰基-D，L-苯丙氨酸盐酸盐的合成与表征 |
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| 引用本文： | 顾准,刘尚莲,倪家宝.邻氰基-D，L-苯丙氨酸盐酸盐的合成与表征[J].化学研究与应用,2008,20(7). |
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| 作者姓名： | 顾准 刘尚莲 倪家宝 |
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| 作者单位： | 健雄职业技术学院化学工程系,江苏,太仓,215400 |
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| 摘 要： | 氨基酸是构成多肽的基本单位,肽链中不同的氨基酸及氨基酸所含基团的不同使其在化学和生物活性等方面有着不同的性质。通过改变肽链中不同氨基酸来修饰肽链的结构和环境,能赋子肽链新的功能。天然氨基酸由于结构的原因,无法满足特殊的需要。随着生物化学合成、分离和测试技术的
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| 关 键 词： | 合成 非天然氨基酸 邻氰基-D L-苯丙氨酸盐酸盐 |
Synthesis and characterization of o-cyano-D,L-phenylalanine hydrochloride |
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| GU Zhun,LIU Shang-lian,NI Jia-bao.Synthesis and characterization of o-cyano-D,L-phenylalanine hydrochloride[J].Chemical Research and Application,2008,20(7). |
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| Authors: | GU Zhun LIU Shang-lian NI Jia-bao |
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| Abstract: | A nonnatural amino acid,o-cyano-D,L-phenylalanine hydrochloride,and its four inter mediates are synthesized using diethyl malonate as raw material.Factors influencing the reaction are studied,the processing methods are improved,and the yield of each reaction is increased.The structure of the compounds mentioned above is determined by IR,NMR,elementary analysis and melting point. |
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| Keywords: | synthesis unnatural amino acid o-cyano-D L-phenylalanine hydrochloride |
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