| 松属素的均匀优化设计法合成研究 |
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| 引用本文： | 程永浩,段亚波,戚燕,童元峰,郭晓赟,杜冠华,吴松.松属素的均匀优化设计法合成研究[J].化学研究与应用,2006,18(11):1334-1335. |
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| 作者姓名： | 程永浩 段亚波 戚燕 童元峰 郭晓赟 杜冠华 吴松 |
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| 作者单位： | 中国医学科学院药物研究所,北京,100050 |
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| 摘 要： | 松属素1](pinocembrin),又名乔松素,化学名5,7-二羟基黄烷酮(5,7-D ihydroxyflavanone)、2,3-二氢-5,7-二羟基-2-苯基-4H-1-苯并吡喃-4-酮(2,3-D ihydro-5,7-d ihydroxy-2-phenyl-4H-1-benzopyran-4-one),是从蜂胶中提取出的一种天然化合物。松属素具有抗菌、抗原虫、抗诱变、
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| 关 键 词： | 5 7-羟基黄酮 5 7-二羟基黄烷酮 钯炭 均匀设计 |
| 文章编号： | 1004-1656（2006）11-1334-02 |
| 收稿时间： | 2006-03-17 |
| 修稿时间： | 2006-05-18 |
Optimizing synthetic method of pinocembrin by uniform experiment design |
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| CHENG Yong-Hao,DUAN Ya-Bo,QI Yan,TONG Yuan-Feng,GUO Xiao-Yun,DU Guan-Hua,WU Song.Optimizing synthetic method of pinocembrin by uniform experiment design[J].Chemical Research and Application,2006,18(11):1334-1335. |
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| Authors: | CHENG Yong-Hao DUAN Ya-Bo QI Yan TONG Yuan-Feng GUO Xiao-Yun DU Guan-Hua WU Song |
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| Institution: | Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College. Beijing 100050, China |
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| Abstract: | 5,7-Dihydroxyflavanone was synthesized by hydrogenation of 5,7-dihydroxyflavone with hydrogen,catalyzed by Pd-C.The reaction conditions were optimized using the method of uniform experiment design to get 84%yield. |
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| Keywords: | 5 7-dihydroxyflavone 5 7-dihydroxyflavanone Pd-C uniform design |
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