| 微波干法合成查尔酮 |
| |
| 引用本文： | 刘兴利,赵志刚,曾碧涛,易奉敏.微波干法合成查尔酮[J].化学研究与应用,2007,19(5):574-576. |
| |
| 作者姓名： | 刘兴利 赵志刚 曾碧涛 易奉敏 |
| |
| 作者单位： | 西南民族大学化学与环境保护工程学院,四川,成都,610041 |
| |
| 摘 要： | 查尔酮的化学名为1,3-二苯基丙烯酮,以它为母体的天然化合物存在于红花、甘草等多种天然植物中,是植物体内合成黄烷酮的重要中间体,其自身也具有抗过敏、抗溃疡、抗肿瘤等药理作用1-3].
|
| 关 键 词： | 微波辐射 查尔酮 固体KF-Al2O3 微波 干法合成 查尔酮 conditions chalcones 药理作用 抗肿瘤 抗溃疡 抗过敏 重要中间体 黄烷酮 植物体内 天然植物 甘草 红花 存在 天然化合物 母体 丙烯酮 二苯基 |
| 文章编号： | 1004-1656（2007）05-0574-03 |
| 收稿时间： | 2007-03-15 |
| 修稿时间： | 2007-04-08 |
Microwave-assisted synthesis of chalcones under solvent-free conditions |
| |
| LIU Xing-li,ZHAO Zhi-gang,ZENG Bi-tao,YI Fen-min.Microwave-assisted synthesis of chalcones under solvent-free conditions[J].Chemical Research and Application,2007,19(5):574-576. |
| |
| Authors: | LIU Xing-li ZHAO Zhi-gang ZENG Bi-tao YI Fen-min |
| |
| Institution: | College of Chemistry and Environmental Protection Engineering, Southwest University for Nationalities, Chengdu 610041, China |
| |
| Abstract: | Using solid KF-Al2O3 as catalyst, nine chalcones were synthesized in good yields by the aldol condensation of 4-nitroacetophenone with aromatic aldehydes in solvent-free conditions under microwave irradiation. Their structures were characterized by ^1H NMR, IR, MS spectra and element analysis. Compared with the conventional method, this method is simple, safe, rapid and eco-friendly. |
| |
| Keywords: | microwave irradiation chalcone solid KF-Al2O3 |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
