| 三七叶甙制备抗癌活性成分20(R)-人参皂甙-Rh2和人参皂甙Rg3 |
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| 引用本文： | 陈业高,黄荣,桂世鸿,吕瑜平,文净.三七叶甙制备抗癌活性成分20(R)-人参皂甙-Rh2和人参皂甙Rg3[J].化学研究与应用,2004,16(1):69-70. |
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| 作者姓名： | 陈业高 黄荣 桂世鸿 吕瑜平 文净 |
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| 作者单位： | 1. 云南师范大学化学系,云南,昆明,650091
2. 云南大学实验中心,云南,昆明,650011 |
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| 基金项目： | 云南省教育厅科学研究基金项目(0111245) |
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| 摘 要： | 人参皂甙-Rh2(ginsenoside Rh2)和Rg3是从人参中分离得到的具有抗癌活性的四环三萜类原人参二醇型低糖链皂甙单体。其中，以人参皂甙为主要成分的抗癌新药Rg3参—胶囊已获国家药品监督管理局颁发的中药一类新药证书。皂甙类成分要从植物中分离困难。为了得到某些活性
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| 关 键 词： | 三七叶甙 抗癌活性成分 20（R）-人参皂甙-Rh2 人参皂甙Rg3 20（s）-人参皂甙Rg3 中药 |
| 文章编号： | 1004-1656(2004)01-0069-02 |
| 修稿时间： | 2003年11月9日 |
Prepapation of 20(R)-ginsenoside Rh2 and Rg3,anticancer principles from leaf saponins of panax notoginseng |
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| CHEN Ye-gao.Prepapation of 20(R)-ginsenoside Rh2 and Rg3,anticancer principles from leaf saponins of panax notoginseng[J].Chemical Research and Application,2004,16(1):69-70. |
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| Authors: | CHEN Ye-gao |
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| Institution: | CHEN Ye-gao~ |
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| Abstract: | 20(R)-ginsenoside-Rh_2,ginsenoside-Rg_3 and 20(S)-ginsenoside Rg_3 were prepared by the hydrolysis of leaf saponins of Panax notoginseng(Burk.)F.H.Chen with solution of 50% acetic acid and then column chromatography on silica gel.Their structures were characterized by spectroscopic analysis,chemical degradation and comparison with authentic samples. |
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| Keywords: | leaf saponins of panax notoginseng hydrolysis 20(R)-ginsenoside-Rh_2 ginsenoside-Rg_3 20(S)-ginsenoside Rg_3 |
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