| 两种色酮膦酸酯类化合物的合成及其结构表征 |
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| 引用本文： | 王俊岭,冯书晓,汪小伟,吴峰敏,谷广娜,马军营.两种色酮膦酸酯类化合物的合成及其结构表征[J].化学研究与应用,2022,34(2):268-273. |
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| 作者姓名： | 王俊岭 冯书晓 汪小伟 吴峰敏 谷广娜 马军营 |
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| 作者单位： | 河南科技大学化工与制药学院,河南洛阳471023 |
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| 摘 要： | 在超声波辐射下,以3-甲酰基色酮,对硝基苯胺和亚磷酸酯为原料,"一锅法"合成了两种含色酮环的α-氨基膦酸酯类化合物,通过IR,1H NMR,13C NMR,31P NMR,ESI-MS对其结构进行了测定和表征.对化合物4a进行了X射线衍射分析,O,O'-二乙基-α-对硝基苯氨基-α-(色酮-4-基)-甲基膦酸酯(4a)(CCDC:2080073)晶体属单斜晶系,C2/c空间群,晶胞参数为a=33.6146(11)(A),b=12.7607(4)(A),c=20.5344(4)(A),β=90.943(3)°,V=8806.9(4)(A)3,Z=16,C21H27N4O3P,Mr=432.36,Dc=1.304g· cm-3,μ=1.484,F(000)=3616,μ(CuKα)=1.54184 mm-1.
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| 关 键 词： | α-氨基膦酸酯 色酮 晶体结构 合成 |
Synthesis and structural characterization of two chromone phosphonate derivatives |
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| WANG Jun-ling,FENG Shu-xiao,WANG Xiao-wei,WU Feng-min,GU Guang-na,MA Jun-ying.Synthesis and structural characterization of two chromone phosphonate derivatives[J].Chemical Research and Application,2022,34(2):268-273. |
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| Authors: | WANG Jun-ling FENG Shu-xiao WANG Xiao-wei WU Feng-min GU Guang-na MA Jun-ying |
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| Abstract: | An ultrasound promoted efficient,environment friendly process had been devised for the synthesis of two novel α-amin-ophosphonates through a one-pot three-component condensation of 3-formylchromone,p-nitroaniline and two different types dialkyl phosphate.The desired products were obtained in excellent yields and in high purity under solvent-free and catalyst-free conditions.Their structures were confirmed by IR,LC-MS and 1H NMR The crystal structure of compounds 4a(CCDC :2080073)was also de-termined by single-crystal X-ray diffraction.It crystallized in monoclinic system,space group C2/c with a =33.6146 (11)(A),b =12.7607(4)(A),c=20.5344(4)(A),β=90.943(3) °,V=8806.9(4)(A)3,Z=16,C20H21N2O7P,Mr=432.36,Dc =1.304g · cm-3,μ=1.484,F(000) =3616.0,CuKα radiation(λ =1.54184(A)). |
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| Keywords: | α-aminophosphonate chromone crystal structure synthesis |
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