|
|||||
|
|
Structural diversity of lanthanide–amino acid complexes under near physiological pH conditions and their recognition of single-stranded DNA |
|
| Authors: | Hai-yuan Zhang Hai-jia Yu Hai-xia Xu Jin-song Ren Xiao-gang Qu |
| Institution: | aDivision of Biological Inorganic Chemistry, Key Laboratory of Rare Earth Chemistry and Physics, Graduate School of the Chinese Academy of Sciences, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China |
| Abstract: | We reported here four structures of lanthanide–amino acid complexes obtained under near physiological pH conditions and their individual formula can be described as Tb2(dl-Cys)4(H2O)8]Cl2 (1), Eu4(μ3-OH)4(l-Asp)2(l-HAsp)3(H2O)7] Cl · 11.5H2O (2), Eu8(l-HVal)16(H2O)32]Cl24 · 12.5H2O (3), and Tb2(dl-HVal)4(H2O)8]Cl6 · 2H2O (4). These complexes showed diverse structures and have shown potential application in DNA detection. We studied the interactions of the complexes with five single-stranded DNA and found different fluorescence enhancement, binding affinity and binding stoichiometry when the complexes are bound to DNA. |
| Keywords: | Lanthanide Ligand–DNA interactions Structure diversity Single-stranded DNA Sequence selectivity |
| 本文献已被 ScienceDirect 等数据库收录！ | |