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Supramolecular polymeric micelles by the host-guest interaction of star-like calix[4]arene and chlorin e6 for photodynamic therapy
Authors:Tu Chunlai  Zhu Lijuan  Li Pingping  Chen Yan  Su Yue  Yan Deyue  Zhu Xinyuan  Zhou Guoyu
Institution:School of Chemistry and Chemical Engineering, State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, 200240, Shanghai, PR China.
Abstract:A supramolecular drug delivery system has been developed via the self-assembly of a supramolecular amphiphilic polymer, which is constructed by the host-guest interaction of hydrophilic PEGylated calix4]arene and hydrophobic photosensitizer chlorin e6. It provides a new strategy for the preparation of supramolecular polymeric micelles, and plays an important role in biological applications.
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