Symmetrical dinuclear complexes with high DNA affinity based on [Ru(dpq)2(phen)]2+ |
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| Authors: | Aldrich-Wright Janice Brodie Craig Glazer Edith C Luedtke Nathan W Elson-Schwab Lev Tor Yitzhak |
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| Institution: | School of Science, Food and Horticulture, College of Science, Technology and Environment, University of Western Sydney, Penrith South, NSW 1797, Australia. J.Aldrich-Wright@uws.edu.au |
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| Abstract: | Symmetrical homometallic dinuclear complexes of the type (Ru(dpq)2)2(phen-SOS-phen)]4+, with a flexible 2-mercaptoethyl ether linker joining the two Ru(dpq)2(phen)]2+-based sub-units, have DNA dissociation constants (Kd) in the nM range. |
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