增塑剂对对二氧环己酮均聚物及共聚物可吸收缝合线结构与性能的影响

以对二氧环己酮均聚物和对二氧环己酮 乙交酯共聚物为原料 ,加入无毒性增塑剂 (邻苯二甲酸酯 )进行纺丝 ,得到聚对二氧环己酮单丝缝合线 (PDS)和对二氧环己酮 乙交酯共聚物单丝缝合线 (PDG) .用DSC、WAXD、声速法对缝合线的结构与性能进行了测试 ,研究了增塑剂含量对缝合线的物理力学性能的影响 .研究结果表明 ,增塑剂使样品的玻璃化转变温度Tg 降低 ,聚合物结晶完善程度降低 .一定含量的增塑剂能够赋予缝合线较好的柔性 ,并使缝合线的初始强度有不同程度的提高

THE EFFECT OF PLASTICIZER ON THE STRUCTURE AND PERFORMANCE OF ABSORBABLE SUTURES MADE WITH POLY(p-DIOXANONE) AND POLY(p-DIOXANONE-co-GLYCOLIDE)

Poly ( p dioxanone) and copolymers of p dioxanone and glycolide were prepared.In order to increasing the plasticity and elasticity of these polymers,nonpoisonous plasticizers(phthalate) were added when they were spun into monofilament absorbable sutures.The polymers were physically admixed with plasticizers under stirring.The structure and properties of poly( p dioxanone) sutures (PDS) and poly( p dioxanone co glycolide) sutures (PDG) were determined by using DSC,X ray diffraction and analyzed through examining the changes of strength,flexibility,macromolecular orientation and the level of crystallinity of the sutures.The introduction of plasticizers may lower the strength of intermolecular forces and increase the flexibility of the polymeric structure.When the plasticizer content was about 1%～4%,the PDS and PDG sutures exhibited improvement both in tensile strength and more flexibility.