| 聚N－烷基丙烯酰胺类凝胶及其温敏特性 |
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| 引用本文： | 金曼蓉,吴长发,张桂英,刘培毅,侯薇.聚N－烷基丙烯酰胺类凝胶及其温敏特性[J].高分子学报,1995,0(3):321-326. |
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| 作者姓名： | 金曼蓉 吴长发 张桂英 刘培毅 侯薇 |
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| 作者单位： | 天津医科大学药学系 300203 |
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| 摘 要： | 研制成功５种聚Ｎ－烷基丙烯酰胺类温敏凝胶：聚Ｎ－异丙基丙烯酰胺（ＰＮＩＰＡ），聚Ｎ－异丙基丙烯酰胺＋甲基丙烯酰胺（ＰＮＩＰＡ／ＭＡＡ），聚Ｎ，Ｎ－二乙基丙烯酰胺（ＰＮＤＥＡ），聚Ｎ－正丙基丙烯酰胺（ＰＮＮＰＡ），聚Ｎ，Ｎ－二乙基丙烯酰胺＋Ｎ－叔丁基丙烯酰胺（ＰＮＤＥＡ／ＮＴＢＡ），并系统研究了这些凝胶的温敏相交特性．以聚Ｎ－异丙基丙烯酰胺（ＰＮＩＰＡ）凝胶相交特性为基础的凝胶萃取过程对牛血清白蛋白和兰葡聚糖溶液的浓缩实验表明，凝胶萃取对于浓缩和制备贵重生化制品是很有效的．
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| 关 键 词： | 烷基内丙烯酰胺 凝胶 温敏性 萃取分离 |
| 收稿时间： | 1993-07-26 |
N-ALKYL ACRYLAMIDE GELS AND THEIR TEMPERATURESENSITIVE PROPERTIES |
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| JIN Man-rong,ZHANG Gui-ying,WU Chang-fa,LIU Pei-yi,HOU Wei.N-ALKYL ACRYLAMIDE GELS AND THEIR TEMPERATURESENSITIVE PROPERTIES[J].Acta Polymerica Sinica,1995,0(3):321-326. |
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| Authors: | JIN Man-rong ZHANG Gui-ying WU Chang-fa LIU Pei-yi HOU Wei |
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| Institution: | Department of Pharmacy; Tianjin Second Medical College.Tianjin 300203 |
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| Abstract: | Poly-N-Alkyl acrylamide temperature-sensitive hydrogels (poly-N-isopropylamide,poly-N-isopropylacrylamide/methylacrylamide copolymer, poly-N, N-die-thylacrylamide,poly-N,N-diethylacrylamide/N-tert-butylactyamide copolymer and poly-N-n-propylamide) have been prepared.The temperature sensibilities,phase -transition as well as swelling-collapsing properties of the gels are discussed. Based on the performances of poly-N-isopropylacrylamide,the gel-extraction separation is examined to be an effective process for concentration of protein solutions. |
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