可聚合脂质体的研究 Ⅰ.含共轭双炔基团的两杂性单体及其脂质体 |
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引用本文: | 李子臣,何巍,李福绵.可聚合脂质体的研究 Ⅰ.含共轭双炔基团的两杂性单体及其脂质体[J].高分子学报,1995,0(1):113-116. |
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作者姓名: | 李子臣 何巍 李福绵 |
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作者单位: | 北京大学化学系 10087l |
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摘 要: | wo aα,w-dipolar amphiphiles, 10, 12-docosadiyne-1, 22-dicarboxylicacid (DDCA) and 10, 12-docosadiyne-1, 22-diol(DDOL)were synthesized by coupling the corresponding 10-undecylcarboxylic acid and 10-undecynol, respectively. They could form hybrid liposomes when ultrasonically dispersed with dimyristoylphosphatidylcholine (DMPC) at equal molar ratio. Liposome formation was confirmed by electron microscopy, UV measurement as well as encapsulation of fluorescent probes. UV irradiation of the mixed liposomes induced the polymerization of DDCA and DDOL on the liposomes, which could be followed by UV-Vis measurement.
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关 键 词: | DDCA 脂质体 DDOL |
收稿时间: | 1993-06-28 |
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