Heteropoly-12-tungstophosphoric acid H3[PW12O40] over natural bentonite as a heterogeneous catalyst for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones |
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Institution: | 1. Department of Chemistry, Krantiguru Shyamji Krishna Verma Kachchh University, Bhuj, Gujarat, India, Vallabh Vidyanagar, India;2. Department Of Chemistry, Sardar Patel University, Vallabh Vidyanagar, India |
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Abstract: | Heteropolyacid 12-tungstophosphoric acid H3PW12O40] (TPA) immobilized over natural bentonite (bent) using the impregnation method. Prepared catalyst were well characterized by XRD, FT-IR and FeSEM. The catalytic activity of three catalysts 10%, 20% and 30% TPA/bent examined for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones known as Biginelli reaction. The catalyst 30% TPA/bent exhibited a high yield of the product towards the synthesis of a variety of dihydropyrimidones (DHPMs). The high yield of dihydropyrimidone (DHPM) was obtained in model reaction in ethanol, acetonitrile and solvent - free condition. The reusability test indicated that 5% of yield of product decreased after 5th cycle. |
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Keywords: | Catalyst dihydropyrimidone reusability |
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